In BD FACSAria III Cell Sorting System the gel coupled cuvette in the flow cell ensures that the system’s lasers are focused precisely on the sample stream and that they generate the greatest signal to maximize the amount of emitted light. It improves collection efficiency and optimizes the resolution needed for multicolor applications, even at high-speed sorting settings.

BD Biosciences claimed that the instrument’s advanced optical system works efficiently to maximize signal detection and increases the sensitivity and resolution for each color in a multicolor assay. Enhanced sensitivity and resolution helps readily identify and sort dim cell populations. In addition, the system’s next-generation flow cell is designed to improve resolution for side population applications and DNA cell cycle analyses.

The system’s new expandable architecture uses an X-mount optical plate that allows the system to be expanded to support up to six laser wavelengths of 633nm, 561nm, 488nm, 445nm, 405nm and 375nm as well as up to 20 detector positions that can be used simultaneously.

It’s backwards-compatible architecture allows customers to upgrade existing instruments to the new BD FACSAria III platform. With a field upgrade, laboratories with a BD FACSAria or BD FACSAria II system can upgrade to the new capabilities of the BD FACSAria III system.

James Glasscock, president of BD Biosciences Cell Analysis, said: “As the pioneer in flow cytometry, BD Biosciences’ goal is to expand the range of applications that can benefit from this technology by building innovative, powerful tools that are easier to use and more accessible to a larger number of life science researchers.

“The new BD FACSAria III system reflects this effort by providing researchers the flexibility to configure a system that meets their application requirements and budgets today, with the ability to expand its capabilities later to meet future needs.”