Microfluidic multiplex devices are used in the analysis of protein biomarkers, biological characteristics that let researchers measure and evaluate normal biological, pathogenic, or pharmacological processes. Microfluidics, the manipulation of small volumes of fluid and flow, is used widely in point-of-care (POC) devices for clinical diagnostics and supports multiplexing, the quantitative measurement of multiple protein biomarkers for complex lab procedures involving cancer or COVID-19. In the case study we will learn how two students at UC Berkeley are 3D printing molds for COVID-19 testing.