Waters has received CE mark approval for its MassTrak Immunosuppressants XE Kit which assesses concentrations of the parent drugs independent of the level of known metabolites in patient samples.
The MassTrak Immunosuppressants XE Solution quantitatively measures tacrolimus (FK506;Prograf) in liver and kidney transplant patients and everolimus (Certican) in adult kidney and cardiac transplant patients.
The kit receives human whole blood samples to assess the drug and facilitates in the management of immunosuppressant drug therapy.
The Waters LC/MS/MS system, a technology for immunosuppressant drug monitoring consists of Immunosuppressants XE Kit.
The LC/MS/MS system with MassTrak Immunosuppressants XE Kit and method, Waters Acquity UPLC UltraPerformance Liquid Chromatography system are coupled with Aacquity TQD tandem quadrupole mass spectrometer which provides enhanced sensitivity and specificity, and measures target compounds at low ng/mL levels (0.5 ng/mL).