As per the agreement, Limbus AI’s Limbus Contour software will be integrated with RefleXion X1 radiotherapy treatment planning system to reduce bottleneck in the patient treatment planning process


A head-and-neck image generated by RefleXion X1 and Limbus Contour. (Credit: Business Wire)

RefleXion Medical has forged a licensing and technology integration agreement with Canada-based Limbus AI, to incorporate artificial intelligence (AI)-based software into radiation treatment planning.

Limbus AI provides software solutions for cancer radiation therapy.

Under the agreement, Limbus AI’s automated contouring software, Limbus Contour, will be integrated with the RefleXion X1 radiotherapy treatment planning system.

RefleXion X1 is a conventional image-guided external-beam radiotherapy. It has been cleared by the US Food and Drug Administration (FDA) for solid tumours situated anywhere in the body.

Limbus Contour uses clinically validated deep-learning segmentation algorithms to minimise human error, ensure exact radiation delivery to target areas, and prevent out-of-area radiation (OARs).

RefleXion, which is a therapeutic oncology company, said that the integration will reduce the bottleneck in the patient treatment planning process. This involves extracting the tumour target from nearby critical organs and other healthy tissue.

RefleXion co-founder and chief technology officer Sam Mazin said: “We have found Limbus Contour’s AI-driven solution to be a technology leader in speed, accuracy and versatility.

“Depending on the complexity of the treatment plan, we expect contouring time reductions of up to 80%, thus ensuring that patients receive timely treatment.

“Furthermore, this sets the stage for adapting the treatment plan immediately prior to delivery to leverage the unique and rich anatomic and biologic information produced by the X1 in image-guided and SCINTIX procedures.”

X1 with SCINTIX biology-guided radiotherapy technology is a dual-treatment modality radiation platform. It has received FDA clearance to treat patients with specified solid tumours of any stage.

Additionally, the benefits of integrating Limbus Contour will extend to biological and anatomic therapeutic techniques, according to RefleXion.

Limbus AI CEO Karl Otto said: “The performance of Limbus Contour software relies on the quality of the CT image.

“X1 images demonstrate high resolution, exceptional contrast, and minimal noise and motion artifacts. This should enhance precision in distinguishing adjacent structures and yield consistent, reliable contouring results, ensuring patients receive the highest quality care possible.”