Proteintech Genomics, a subsidiary of Proteintech Group, Inc., and a provider of multiomic solutions for single-cell and spatial analysis, announced the launch of the MultiPro™ Human Fixed Cell Immune Profiling Antibody Cocktail. This cocktail contains 53 antibodies against intracellular and cell surface proteins, plus 5 isotype controls. The pre-titrated cocktail is demonstrated to be compatible with the 10x Genomics® Chromium® Single Cell Gene Expression Flex product.
CEO of Proteintech Genomics, Kit Nazor, states, “With techniques like CITE-seq, it has been possible to layer highly multiplexed cell surface protein data on top of single cell gene expression profiles, but intracellular proteins have remained out of reach. We have been working diligently to provide researchers with the ability to delve beyond the cell surface and provide a high resolution view of intracellular proteins in addition to cell surface proteins and gene expression. Our MultiPro™ antibodies will empower researchers to push the boundaries of what we can learn from single cell studies.”
Peter Smibert, VP of Biology at 10x Genomics, said, “In my pre-10x days, my lab developed CITE-seq to measure surface proteins with single cell transcriptomes. While several groups have subsequently obtained believable signal from intracellular proteins coupled with single cell gene expression, the resulting data was suboptimal. Proteintech Genomics’ MultiPro Immune Profiling Cocktail together with 10x’s Chromium Single Cell Gene Expression Flex assay is a game changer, unlocking protein detection throughout the whole cell – surface, cytoplasm and nucleus – and delivered with the high-quality gene expression data we expect from Flex.”
Source: Company Press Release
