The Olympus IX81 microscope system combines with the ZDC2 Z-Drift compensation module to provide automatic focal adjustment.
Olympus said the new Z-Drift compensation system continually monitors the distance between the objective lens and the sample surface, thus maintaining accurate focus during even the fastest time-lapse experiments.
The new mode is also ideal for more complex applications, such as total internal reflection microscopy (TIRFM).
For longer time-lapse studies, the ‘one-shot’ mode can be employed, maintaining accurate focus for hours, days or even weeks at a time.
The ZDC2 employs an infrared laser diode to locate the interface between the slide cover slip and the surrounding media.
As the relationship between the sample and the cover slip tends to be consistent, this allows the microscope system to remain focused in response to external factors, via the rapid adjustment of the nosepiece.
The complete system is compatible with a range of powerful Olympus hardware and software, including cellSens Dimension and xcellence, as well as integrating fully with environmentally-isolated stage incubation systems.