IntelliCyt, a provider of high throughput cell and bead-based screening products for life science research, has introduced a new Flow Cytometry HTFC Screening System at the 25th International Society for advancement of Cytometry in Seattle.
IntelliCyt said that the new HTFC Screening System, designed to enable large scale, high throughput, high content screening, takes a new approach to cell-based screening by integrating the company’s HyperCyt technology and flow cytometry. The flow cytometry is the sensitive technology for measuring fluorescent markers on cells in suspension with HyperCytPRO, IntelliCyt’s advanced server-based informatics platform.
The result is a simple screening system that enables researchers to cost effectively perform broader experiments with more controls and replicates, screen more compounds, and analyze data in ways never before possible with conventional flow cytometry.
According to IntelliCyt, using the HTFC Screening System, researchers can analyze multiparameter cell populations or multiplexed bead suspensions in 96- and 384-well microplates at rates up to 40 wells per minute, capturing data on thousands of cells per second. Because the HTFC Screening system can accommodate very small specimens, sample and reagent requirements are reduced by 50 to 90%, resulting in significant cost savings.
The heightened sensitivity and multicolor capabilities of the flow cytometer detection system also enable additional applications, including antibody screening, cytotoxicity studies and biomarker analysis.
Terry Dunlay, president and CEO of IntelliCyt, said: “The HTFC Screening System represents a significant breakthrough in high content screening because it broadens the types of cells and multiplexed assays that can be used for testing compounds in drug discovery research. By coupling our high-throughput sampler with the large dynamic range and multiplexing capability of flow cytometry-based detectors, the HTFC Screening System provides scientists with powerful advantages over other currently available technologies.”