Nordhoff, who has led Gen-Probe since 1994, will become non-executive chairman upon his re-election to the board by stockholders at the company’s 2009 annual meeting.

“I’m delighted to announce the board’s unanimous election of Carl as Gen-Probe’s next CEO,” Nordhoff said. “He brings unparalleled experience in our field and a deep understanding of molecular diagnostics. His keen intellect and unflagging energy will prove invaluable as he takes the helm of the Company.”

“In nearly 15 years as CEO of Gen-Probe, Hank has presided over tremendous business growth, product innovation and shareholder value creation,” said Armin Kessler, Gen-Probe’s lead independent director and former chief operating officer of Hoffman-La Roche. “The Company has grown from a subsidiary of Chugai, with $61 million in annual revenues, to a public company with a market capitalization exceeding $2 billion and revenues of $473 million last year. Gen-Probe’s customers, employees and shareholders owe him a debt of gratitude, and the board is fortunate to be able to continue benefiting from his guidance and leadership.”