Rockland’s product portfolio provides well characterized and sensitive generic reagents for immunodetection of host cell proteins as well as multiple customizable options for process-specific HCP antibody development as a service.
These options allow flexibility and control to the sponsor for developing early stage through late stage HCP detection reagents.
- Standard Host Cell Protein Antibody Reagent Generation Using total or fractionated high molecular weight (HMW) and low molecular weight (LMW) HCP extract fractions.
- Cascade Host Cell Protein Antibody Reagent Generation Cascade immunoprecipitation and immunization to produce broad comprehensive HCP coverage
- Host Cell Protein Antibody Reagent Characterization: ELISA Testing, 1D SDS-PAGE with Western Blotting, 2D SDS-PAGE with Western Blotting and Coverage Assessment, Assay Development and GeLC-MS/MS