RTI Biologics, Inc announced that it will be completing the study of CR-Plug by November 2010.
CR Plug is a human bone allograft used to fill the hole and repair the defects created at the harvest site during the Osteochondral Autograft Transfer System(OATS) procedure. The CR-Plug is a sterile biomaterial product consisting entirely of human allograft bone tissue.
The objective of this study is to determine how effective a plug made out of human bone (called CR-Plug) will be in the treatment at the site that your tissue was removed, thereby filling the hole created during the OATS procedure. At the present, OATS is used for knee articular cartilage defects or injuries smaller than the size of a dime (or 2.5 cm2) in the areas that bear weight have been commonly treated by using a tiny cylinder of the subjects’ own tissue called an osteochondral autograft (OATS).
This 15 patient, phase III study is currently recruiting participants. The official title of the study is “Evaluation of the Composite of Cancellous and Demineralized Bone Plug (CR Plug) for Repair of Defects Created at the Harvest Site During the Osteochondral Autograft Transfer System(OATS)Procedure”.