An analysis of data from 34 patients who had invasive angiography and a nuclear stress test showed that Adenosine stress computed tomography (CT) accuracy will be same in determining stress-induced myocardial perfusion defects as single-photon emission computed tomography (SPECT).

This research was published in the September 15, 2009 issue of the Journal of the American College of Cardiology.

Ron Blankstein, M.D., of the Massachusetts General Hospital and Harvard Medical School in Boston, and colleagues involved in this study.

On a per-vessel basis, the researchers found that CT perfusion had 79% sensitivity and 80% specificity in finding stenosis of at least 50% on invasive angiography while SPECT myocardial perfusion imaging had 67% sensitivity and 83% specificity. CT angiography during adenosine showed 96% sensitivity and 73% specificity for finding stenosis of at least 70% on invasive angiography.