The patented TruTip approach uses a nucleic acid binding matrix that is easily inserted into most standard pipette tips, including those used by electronic pipettes and liquid handling robotic devices. By passing sample back and forth across the binding matrix, in a few short steps TruTip delivers inhibitor-free, PCR-ready nucleic acid from a variety of sample types, including blood, plasma, sputum, urine, and challenging matrices such as soil or water. The platform works equally well with both DNA and RNA isolated from viruses, bacteria or animals.

“The TruTip approach is truly groundbreaking in that it is 10-fold faster than current methods and doesn’t require centrifugation, spin column, or magnetic bead separation,” stated Dr. David Pawlowski, Senior Research Scientist at CUBRC, Inc. and Research Assistant Professor of Microbiology and Immunology in the School of Medicine and Biomedical Sciences at the State University of New York at Buffalo. Dr. Pawlowski adds, “Productivity is easily increased by an order of magnitude compared to other techniques as TruTip simplifies one of the most difficult parts of the molecular assay process – reliably and rapidly extracting inhibitor free, PCR-ready material.”

The TruTip product line currently includes kits for genomic DNA, microbial DNA, and RNA extraction from a variety of sample sources. Additional products are in the development pipeline for release in early 2010.